Self-host OpenELIS Global
3.3.0Open-source lab information system for clinical labs
- Stars
- 278
- Ports
- 8080 (Backend webapp HTTP), 8443 (Backend webapp HTTPS)
What is OpenELIS Global?
OpenELIS Global is an enterprise-grade Laboratory Information System built for public health laboratories operating at national scale. The software automates laboratory work plans, imports results from clinical analyzers, and handles complex workflows including pathology, cytology, and environmental testing with compliance evaluation. It uses FHIR R4 as its native standard for interoperability with other health systems, satisfies ISO and SLIPTA accreditation criteria, and connects to laboratory instruments through ASTM, HL7, and CSV protocols. The platform tracks specimens through sample storage and chain-of-custody features, manages pathology cases from grossing to sign-out, and provides One Health surveillance across human, animal, and environmental health domains in a single system. Deployment is via Docker Compose using published container images, with an offline installer available for air-gapped environments. A public demo instance runs at demo.openelis-global.org. The project is maintained by the Digital Initiative Group at the University of Washington and released under the Mozilla Public License 2.0.
Should you self-host OpenELIS Global?
OpenELIS Global scores 54/100 on selfhost.directory (how scoring works) and ranks #3 of 5 in Healthcare. It has 278 GitHub stars.
It shipped 8 stable releases in the past year. The latest, 3.3.0, came out on 20 October 2026. New versions land roughly every 4 weeks.
Setup is moderate: expect some configuration beyond a single command. It is MPL-2.0-licensed and written mostly in Java.
Its closest alternative on selfhost.directory is OpenEMR (72/100, 5 555 stars). It scores higher overall, so compare the two before you pick. See OpenELIS Global vs OpenEMR side by side.
Features
- Analyzer integration
- Electronic signatures
- Environmental testing with compliance evaluation
- FHIR R4 native
- ISO/SLIPTA accreditation support
- Laboratory Information System (LIS/LIMS)
- Live demo
- Multi-language Support
- One Health surveillance
- Pathology & Histopathology
- REST API
- Sample storage & chain of custody
- Single Sign-On (SSO)
- Work plan automation
OpenELIS Global README
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