Self-hosted apps that integrate with Let's Encrypt (ACME)

6 open-source, self-hostable projects list Let's Encrypt (ACME) as an integration.

• IncusSelf-hosted, open-source system container and VM manager with unified REST API for local and remote management, scaling from single machine to clusters.
• filestashSelf-hosted, open-source web file manager that puts S3, SFTP, WebDAV, SMB, FTP and around 20 more storage protocols behind one Dropbox-style interface.
• defguardSelf-hosted WireGuard VPN platform bundling an identity provider, per-connection MFA, LDAP/AD sync and firewall ACLs; open-source AGPL core written in Rust.
• fn-knockSelf-hosted gateway that combines reverse proxy, authentication, WAF, SSL certificates, DDNS, and tunneling for home servers and NAS devices.
• LucX-UILucX-UI is a self-hosted Xray VPN panel forked from 3x-ui adding kernel-mode AmneziaWG, tunnel sidecars, and advanced subscriptions.
• MobazhaSelf-hosted open-source P2P commerce platform where sellers own their storefront and data, connecting to shared marketplaces with multi-chain crypto payments.