# agent-second-brain vs AnythingLLM

> Two self-hosted [AI Assistant projects](https://selfhost.directory/ai-assistant), compared on the numbers selfhost.directory tracks live: score, popularity, release cadence and setup effort.

| | agent-second-brain | AnythingLLM |
|---|---|---|
| Score | 50/100 | 88/100 ✓ |
| Rank in category | #40 of 120 in AI Assistant | #2 of 120 in AI Assistant |
| GitHub stars | 411 | 67 682 ✓ |
| Stars, last 30 days | — | +1 296 |
| Stable releases, 12 months | 6 | 18 ✓ |
| Latest release | v3.0.3 · 20 Jun 2026 | v1.19.0 · 26 Oct 2026 ✓ |
| Setup | Advanced | Moderate ✓ |
| Official Docker image | No | Yes ✓ |
| License | MIT | MIT |
| Main language | Python | JavaScript |

## Which one should you pick?

AnythingLLM scores 88/100 against 50/100 for agent-second-brain, so it is the safer default.

AnythingLLM ships more often: 18 stable releases in the past year, against 6 for agent-second-brain.

If you want the quickest setup, AnythingLLM is easier to run; agent-second-brain needs more configuration.

AnythingLLM is growing faster right now (+1 296 stars in 30 days).

## Details

- [agent-second-brain](https://selfhost.directory/project/agent-second-brain) (markdown: https://selfhost.directory/project/agent-second-brain.md)
- [AnythingLLM](https://selfhost.directory/project/anythingllm) (markdown: https://selfhost.directory/project/anythingllm.md)

## Related comparisons

- [AnythingLLM vs meetily](https://selfhost.directory/compare/anythingllm-vs-meetily)

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Source: https://selfhost.directory/compare/agent-second-brain-vs-anythingllm