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agent-second-brainvsAnythingLLM

Two self-hosted AI Assistant projects, compared on the numbers selfhost.directory tracks live: score, popularity, release cadence and setup effort.

agent-second-brainAnythingLLM
Score50/10088/100
Rank in category#40 of 120 in AI Assistant#2 of 120 in AI Assistant
GitHub stars41167 679
Stars, last 30 days—+1 293
Stable releases, 12 months618
Latest releasev3.0.3 · 20 Jun 2026v1.19.0 · 26 Oct 2026
SetupAdvancedModerate
Official Docker imageNoYes
LicenseMITMIT
Main languagePythonJavaScript

Which one should you pick?

AnythingLLM scores 88/100 against 50/100 for agent-second-brain, so it is the safer default.

AnythingLLM ships more often: 18 stable releases in the past year, against 6 for agent-second-brain.

If you want the quickest setup, AnythingLLM is easier to run; agent-second-brain needs more configuration.

AnythingLLM is growing faster right now (+1 293 stars in 30 days).

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