# Self-hosted alternatives to OpenAI Assistant API

> 1 self-hostable, open-source alternative to OpenAI Assistant API, ranked by score.

- [open-assistant-api](https://selfhost.directory/project/open-assistant-api)

## Also in AI Assistant

Not listed as OpenAI Assistant API alternatives, but from the same category:

- [OpenOpenAI](https://selfhost.directory/project/openopenai): OpenOpenAI is a self-hosted, open-source OpenAI Assistants API implementation wire-compatible with official SDKs for custom models and RAG.
- [nova](https://selfhost.directory/project/nova): Self-hosted personal AI with a measured memory loop and 70+ autonomous monitors building living dossiers — all local, zero cloud.
- [Khoj](https://selfhost.directory/project/khoj): Self-hosted, open-source AI second brain: RAG chat over your notes and the web, custom agents, semantic search and scheduled research emailed to you.
- [MindGenius AI](https://selfhost.directory/project/mindgeniusai): A self-hosted AI agent that reads PDFs and creates editable mind maps on your own hardware — your documents and API keys stay local.
- [hermes-agent](https://selfhost.directory/project/hermes-agent): Self-hosted open-source AI agent that learns from experience, creates skills, runs on Telegram, Discord, Slack, CLI — MIT licensed.
- [AnythingLLM](https://selfhost.directory/project/anythingllm): AnythingLLM is a self-hosted, open-source AI app for document chat, AI agents, and local/cloud LLMs — running on your hardware with no token limits.

All 257 AI Assistant projects: https://selfhost.directory/ai-assistant

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Source: https://selfhost.directory/alternative-to/openai-assistant-api